~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Metabolic Syndrome, Diabetes, and Insulin Resistance October 22, 2015 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Greetings Friends of Bio-Alternatives, Magnesium deficiency has been found to be a significant independent risk factor for the development of type 2 diabetes. Multiple studies indicate that as many as half of type 2 diabetics are low in magnesium, with research further showing that low magnesium levels are a significant contributing factor in many complications of the disease. Additional clinical studies, however, have shown that oral supplementation of magnesium to non-diabetic individuals with low magnesium status improved insulin sensitivity and reduced the risk of developing diabetes. In a December 2010 study published in Diabetes Care following 4,497 American young adults between ages 18 and 30 with no diabetes at baseline, Dr. Dae Jung Kim and colleagues from the UNC Gillings School of Global Public Health and School of Medicine investigated the relationship between magnesium intake and incidence of diabetes and insulin resistance. Participants were divided into quintiles based on dietary magnesium intake, and followed for 20 years. During this period, 330 individuals developed diabetes. The research team found magnesium intake to be inversely associated with the incidence of diabetes, to the point that those in the highest intake of magnesium intake were only about half as likely to develop diabetes as those in the lowest intake of magnesium . Furthermore, serum levels of magnesium were significantly inversely correlated with insulin resistance (as indicated by HOMA-IR) and measures of inflammation, including high-sensitivity C-reactive protein (hs-CRP). To further highlight the role of magnesium for optimal insulin sensitivity, in a study published in Diabetes, Obesity, and Metabolism in 2011, Dr. Frank Christoph Mooren and colleagues from the Institute of Sport Sciences at Justus-Liebig University in Germany assessed the benefits of oral magnesium supplementation in non-diabetic but overweight metabolic syndrome patients (30 to 70 years of age) who had normal magnesium levels at baseline. Patients were randomized to receive magnesium, or placebo, daily for six months. | |
| In the group supplemented with magnesium, significant improvements were noted compared to the placebo group, in fasting blood sugar and measures of insulin sensitivity. This study indicated the importance of optimizing magnesium status even in those insulin-resistant individuals with normal magnesium levels. In another study published in 2011 in the European Journal of Clinical Investigation, magnesium supplementation was associated with a significantly improved ability of pancreatic beta-cells to compensate for decreases in insulin sensitivity. The randomized, double-blind clinical study by Fernando Guerrero-Romero and Martha Rodrıguez-Moran, both of whom are affiliated with The Research Group on Diabetes and Chronic Illnesses in Durango, Mexico, involved non-diabetic individuals with normal blood pressure and low serum magnesium levels who were supplemented with magnesium for three months, or allocated to the placebo group. Baseline measurements of beta-cell function were the same in both groups. No lifestyle modifications or other treatments were given during the study.
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| At the end of the three-month study period, the group supplemented with magnesium had a significantly improved ability of their pancreatic beta-cells to compensate for decreases in insulin sensitivity. The individuals supplemented with magnesium also had significantly reduced systolic and diastolic blood pressure, fasting plasma glucose, and fasting insulin levels compared with those in the placebo group. This study is significant because it found that even in apparently healthy individuals with low magnesium status, oral magnesium supplementation was able to induce improvements in beta-cell function and enhance insulin efficiency.
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| If you think magnesium is something you would like to add to your supplement regimen Bio-Alternatives has both a bulk powder and an encapsulated form for you to choose from. Both are highly Bio-Available. CLICK HERE to learn about MAGNESIUM CITRATE (Bulk Powder) | |
| Contact Information ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ email: sales@bio-alternatives.net phone: 866-882-0213 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ |
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