MedicalConspiracies- Drugs that cause liver damage - you will be shocked!!!

Drugs that cause liver damage - You will be shocked!!!

http://www.hepcnet.net/drugsandliverdamage.html

 
DRUGS THAT MAY CAUSE LIVER DYSFUNCTION OR DAMAGE

The liver is the principal organ that is capable of converting drugs into forms that can be readily eliminated from the body. Given the diversity in use today and the complex burden they impose upon the liver, it is not surprising that a broad spectrum of adverse drug's effects on liver functions and structures has been documented. The reactions range from mild and transient changes in the results of liver function tests to complete liver failure with death of the host. Many drugs may affect the liver adversely in more than one way, as cited below in several listings. The use of the following drugs requires careful monitoring of their effects on the liver during the entire course of treatment.

This list is just a general guideline. Many drugs affect the liver to one degree or another and we can't list all of them here; new drugs are always being approved for general use. Read the accompanying literature with your prescriptions and always consult with your doctor or pharmacist about any new medication if you have liver disease!

Drugs that may cause ACUTE DOSE-DEPENDENT LIVER DAMAGE
(resembling acute viral hepatitis)

• acetaminophen
• salicylates (doses over 2 grams daily)

Drugs that may cause ACUTE DOSE-INDEPENDENT LIVER DAMAGE
(resembling acute viral hepatitis) 

acebutolol indomethacin phenylbutazone allopurinol isoniazid phenytoin atenolol ketoconazole piroxicam carbamazepine

labetalol probenecid cimetidine maprotiline pyrazinamide dantrolene metoprolol quinidine diclofenac mianserin

quinine diltiazem naproxen ranitidine enflurane para-aminosalicylic acid sulfonamides ethambutol penicillins sulindac

ethionamide phenelzine tricyclic antidepressants halothane phenindione valproic acid ibuprofen phenobarbital verapamil

Drugs that may cause ACUTE FATTY INFILTRATION OF THE LIVER

adrenocortical steroids phenothiazines sulfonamides antithyroid drugs phenytoin

tetracyclines isoniazid salicylates valproic acid methotrexate

Drugs that may cause CHOLESTATIC JAUNDICE 

actinomycin D chlorpropamide erythromycin amoxicillin/clavulanate cloxacillin flecainide azathioprine cyclophosphamide flurazepam captopril cyclosporine flutamide

carbamazepine danazol glyburide carbimazole diazepam gold cephalosporins disopyramide griseofulvin chlordiazepoxide enalapril

enalapril haloperidol ketoconazole norethandrolone sulfonamides mercaptopurine oral contraceptives tamoxifen methyltestosterone oxacillin thiabendazole

nifedipine penicillamine tolbutamide nitrofurantoin phenothiazines tricyclic antidepressants nonsteroidal phenytoin troleandomycin anti-inflammatory drugs propoxyphene verapamil

Drugs that may cause LIVER GRANULOMAS (chronic inflammatory nodules) 

allopurinol gold phenytoin aspirin hydralazine procainamide carbamazepine isoniazid quinidine chlorpromazine

isoniazid quinidine chlorpromazine nitrofurantoin sulfonamides diltiazem penicillin tolbutamide disopyramide phenylbutazone

Drugs that may cause CHRONIC LIVER DISEASE

Drugs that may cause active chronic hepatitis

• acetaminophen (chronic use, large doses)
• dantrolene
• methyldopa
• isoniazid
• nitrofurantoin

Drugs that may cause liver cirrhosis or fibrosis (scarring)

• methotrexate
• terbinafine HCI (Lamisil, Sporanox)

• nicotinic acid

Drugs that may cause chronic cholestasis (resembling primary biliary cirrhosis)

• chlorpromazine/valproic acid (combination)
• imipramine
• thiabendazole
• phenothiazines
• tolbutamide
• chlorpropamide/erythro-mycin (combination)
• phenytoin

Drugs that may cause LIVER TUMORS (benign and malignant)

• anabolic steroids
• oral contraceptives
• thorotrast
• danazol
• testosterone

Drugs that may cause DAMAGE TO LIVER BLOOD VESSELS

• adriamycin
• dacarbazine
• thioquanine
• anabolic steroids
• mercaptopurine
• vincristine
• azathioprine
• methotrexate
• vitamin A (excessive doses)
• carmustine
• mitomycin
• cyclophosphamide/cyclo-sporine (combination)
• oral contraceptives