MedicalConspiracies- 100 mg aspartame in 250 ml can Red Bull gives 11 mg methanol -- co-factor in harm in an hour for blood platelet and endothelial function? MI Worthley, SR Willoughby, P Sanders, Adelaide, Australia 2010: Rich Murray 2013.10.29 (More on Red Bull issue lawsuit)

From: Dr. Betty Martini,D.Hum. <bettym19@mindspring.com>;
To: <bettym19@mindspring.com>;
Subject: [Health_and_Healing] about 100 mg aspartame in 250 ml can Red Bull gives 11 mg methanol -- co-factor in harm in an hour for blood platelet and endothelial function? MI Worthley, SR Willoughby, P Sanders, Adelaide, Australia 2010: Rich Murray 2013.10.29 (More on Red Bull issue lawsuit)
Sent: Wed, Oct 30, 2013 4:19:21 PM

about 100 mg aspartame in 250 ml can Red Bull gives 11 mg methanol -- co-factor in harm in an hour for blood platelet and endothelial function? MI Worthley, SR Willoughby, P Sanders, Adelaide, Australia 2010: Rich Murray 2013.10.29 http://rmforall.blogspot.com/2013/10/about-100-mg-aspartame-in-250-ml-can_30.html Red Bull's 100 mg aspartame gives 11 mg methanol (wood alcohol), made into uncontrolled formaldehyde by ADH1 enzyme inside cells of inner walls of blood vessels -- co-factor in early vascular diseases -- WC Monte paradigm: Rich Murray 2013.10.29 [ Red Bull energy drink also uses Ace-K sweetener in its 8.4 oz can. ] Scott R. Willoughby <scott.willoughby@adelaide.edu.au>, Prashanthan Sanders <prash.sanders@adelaide.edu.au>, Matthew I. Worthley  <matthew.worthley@adelaide.edu.au>, Jonathan M. Schott <jschott@dementia.ion.ucl.ac.uk>, http://www.amjmed.com/article/S0002-9343(09)00874-2/abstract The American Journal of Medicine Volume 123, Issue 2 , Pages 184-187, February 2010 Detrimental Effects of Energy Drink Consumption on Platelet and Endothelial Function Matthew I. Worthley, MBBS, PhD, <matthew.worthley@adelaide.edu.au>, Anisha Prabhu, BSc(Hons), Paolo De Sciscio, BHSci(Hons), Carlee D. Schultz, BHSci, Prashanthan Sanders, MBBS, PhD, <prash.sanders@adelaide.edu.au>, Scott R. Willoughby, PhD Department of Cardiology, Cardiovascular Research Centre, Royal Adelaide Hospital, and Disciplines of Physiology and Medicine, University of Adelaide, Adelaide, Australia http://www.theswedishyogi.com/?p=139 Tove Chamness Why I wonтРЩt let my husband drink Red Bull September 24, 2013 by admin in Nutrition, Uncategorized No Comments - See more at: http://www.theswedishyogi.com/?p=139#sthash.A1Fv54A7.dpuf In 2008, there was one study done in Australia that tested 50 university students aged 18-30. Dr Scott Willoughby, who led the study, said: "One hour after they drank Red Bull, (their blood systems) were no longer normal. One hour after drinking a Sugarfree Red Bull, the participants showed blood test results that was to be expected in 'someone with cardiovascular disease'. Their blood had become тРЬstickyтРЭ and much slower flowing." Dr Willoughby, of the Cardiovascular Research Centre at the Royal Adelaide Hospital, was тРШalarmedтРЩ at the results and would not drink Red Bull himself. This is albeit a small study, and no larger or similar study has been done since (to my knowledge), nevertheless, I think the results are certainly noteworthy even though Red Bull reps denied the results as significant. http://www.dailymail.co.uk/health/article-1045195/Red-Bull-gives---increased-risk-heart-disease-say-scientists.html#ixzz2fHdQ56k1 Red Bull gives you.... increased risk of heart disease, say scientists By FIONA MACRAE UPDATED: 17:50 EST, 15 August 2008 http://www.dailymail.co.uk/health/article-1045195/Red-Bull-gives---increased-risk-heart-disease-say-scientists.html#ixzz2jB6tTMvo Just one can of Red Bull could raise the risk of heart attack or stroke, even in young people, researchers have warned. A study of university students found drinking one 250 ml can of the sugar-free version of the energy drink that 'gives you wings' increased the 'stickiness' of the blood and raised the risk of life-threatening clots. Researcher Dr Scott Willoughby said: "One hour after they drank Red Bull, (their blood systems) were no longer normal." Red Bull Health doubts: Sugar-free Red Bull "They were abnormal like we would expect in a patient with cardiovascular disease. If you get an increase in stickiness and a decreased ability of the blood vessels to stop its stickiness, that adds up to a bad situation. If you add in other risk factors for cardiovascular disease - stress or high blood pressure - this could be potentially deadly." Dr Willoughby, of the Cardiovascular Research Centre at the Royal Adelaide Hospital, said he was 'alarmed' at the results and would not drink Red Bull himself. Those with underlying heart or circulatory problems should think twice before buying the caffeine-loaded drink, he said. The results, reported in the Australian newspaper, also shocked the students taking part, some of whom drank up to eight cans a night to help them stay awake to study.  Many now refuse to drink Red Bull again. Red Bull is banned in Norway, Uruguay and Denmark because of health fears, but the company last year sold 3.5 billion cans and bottles in 143 countries. In Britain alone, it has sales of â"¬Ð³271 million a year, with much of the cash spent in bars and clubs were it is a popular mixer with vodka and other spirits. Previous studies have warned the stimulant effect of Red Bull can mask some of the tell-tale signs of drunkenness -- putting revellers at risk of injury and attack because they do not realise how intoxicated they are. Red Bull Dr Willoughby said drinking Red Bull caused the blood 'to become sticky' The Australian researchers said that two of the drink's ingredients -- caffeine and the amino acid taurine -- may have dangerous consequences for the heart when taken together. Dr Willoughby said: "Caffeine and taurine -- both of these individually point towards being beneficial but maybe there's something quirky about the effect of the combination of the two that is causing this reaction, that is what we need to look at next." Formulated by the marketing director of an Austrian toothpaste company in the 1980s, one can contains 80 mg of caffeine, around the same as a cup of filter coffee, or two cups of instant. However, cans do carry health warnings advising people not to drink more than two a day. Red Bull Australia spokeswoman Linda Rychter said: 'The study does not show effects which would go beyond drinking a normal cup of coffee. She added that Red Bull's global sales were testament to health authorities across the world concluding it was safe to drink. But Dr Willougby said: "If you have any predisposition to cardiovascular disease, I'd think twice about drinking it." http://www.dailymail.co.uk/health/article-1045195/Red-Bull-gives---increased-risk-heart-disease-say-scientists.html#ixzz2jB7akMla http://www.heartfoundation.org.au/sites/researchnetwork/Researchers/Pages/Willoughby%20Scott.aspx Scott R. Willoughby [ photo ] Cardiovascuar Investigation Unit Royal Adelaide Hospital Adelaide SA 5000 Phone : 08 8303 0131 Email : scott.willoughby@adelaide.edu.au Qualifications PhD Current Projects : Left atrial platelet function in atrial fibrillation Effect of energy drinks on platelet and endothelial function Does childhood sleep disorder breathing increase future risk of cardiovascular disease? Research Interests : Thrombogenesis Vascular function http://www.amjmed.com/article/S0002-9343(09)00874-2/abstract The American Journal of Medicine Volume 123, Issue 2 , Pages 184-187, February 2010 Detrimental Effects of Energy Drink Consumption on Platelet and Endothelial Function Matthew I. Worthley, MBBS, PhD, <matthew.worthley@adelaide.edu.au>, Anisha Prabhu, BSc(Hons), Paolo De Sciscio, BHSci(Hons), Carlee D. Schultz, BHSci, Prashanthan Sanders, MBBS, PhD, <prash.sanders@adelaide.edu.au>, Scott R. Willoughby, PhD Department of Cardiology, Cardiovascular Research Centre, Royal Adelaide Hospital, and Disciplines of Physiology and Medicine, University of Adelaide, Adelaide, Australia Abstract Background Energy drink consumption has been anecdotally linked with sudden cardiac death and, more recently, myocardial infarction. As myocardial infarction is strongly associated with both platelet and endothelial dysfunction, we tested the hypothesis that energy drink consumption alters platelet and endothelial function. Methods Fifty healthy volunteers (34 male, aged 22â"¬â–'2 years) participated in the study. Platelet aggregation and endothelial function were tested before, and 1 hour after, the consumption of 250 mL (1 can) of a sugar-free energy drink. Platelet function was assessed by adenosine diphosphate-induced (1 â"œÐ¼mol/L) optical aggregometry in platelet-rich plasma. Endothelial function was assessed via changes in peripheral arterial tonometry and expressed as the reactive hyperemia index (RHI). Results Compared with baseline values, there was a significant increase in platelet aggregation following energy drink consumption, while no change was observed with control (13.7â"¬â–'3.7% vs 0.3â"¬â–'0.8% aggregation, respectively, P <.01). Similarly, RHI decreased following energy drink consumption ( 0.33â"¬â–'0.13 vs 0.07â"¬â–'0.12 RHI [control], P <.05). Mean arterial pressure significantly increased following energy drink consumption, compared with control (P <.05). Heart rate was unaffected by energy drink consumption. Conclusion Energy drink consumption acutely increases platelet aggregation and decreases endothelial function in healthy young adults. PMID: 20103032 Keywords: Endothelial function, Energy drinks, Myocardial infarction, Platelet aggregation, Sudden cardiac death Funding: Dr. Sanders is supported by the National Heart Foundation of Australia.  Conflict of Interest: No author has a conflict of interest with this work.  Authorship: All authors have had access to the data and a role in the manuscript. PII: S0002-9343(09)00874-2 doi:10.1016/j.amjmed.2009.09.013 â"¬Ð¹ 2010 Elsevier Inc. All rights reserved. Heart, Lung and Circulation Volume 18, Supplement 3 , Page S265, 2009 Energy drink effects platelet aggregation and endothelial function: A possible link to increased cardiovascular risk Scott R. Willoughby, Paolo De Sciscio, Anisha Prabhu, Ross Roberts-Thomson, Carlee Schultz, Prashanthan Sanders, Matthew Worthley Cardiovascular Research Centre, Department of Cardiology, Royal Adelaide Hospital and the Disciplines of Physiology and Medicine, University of Adelaide, Adelaide, South Australia, Australia PII: S1443-9506(09)00849-X doi:10.1016/j.hlc.2009.05.653 â"¬Ð¹ 2009 Published by Elsevier Inc. Methanol (wood alcohol) from cigarettes and aspartame circulates with blood half-life 3 hours, entering every cell -- made into uncontrolled formaldehyde inside cells with high ADH1 enzyme levels -- WC Monte paradigm: Rich Murray 2013.10.28 Only humans cells lack a functioning biochemical defense against the ADH1 enzyme, in high levels in 20 tissues, rapidly making methanol into uncontrolled, free floating highly reactive acidic hydrated formaldehyde right inside the cytosol. Thus, humans are ten to a hundred times more vulnerable than any other creature. similar macular harm in multiple sclerosis as from formaldehyde made by ADH enzyme inside retina capillary walls from methanol, Prof. Woodrow C. Monte text "While Science Sleeps" 2012 Jan -- some quotes re retina harm: Rich Murray 2012.05.10 http://rmforall.blogspot.com/2012/05/similar-macular-harm-in-multiple.html Evidence exists that autism results from exposure to pregnant women in the fourth week, since ADH1 levels are high in the Purkinje cells of the vermis in the cerebellum, while other plausible birth defects include spina bifida, premature birth, and Fetal Alcohol Spectrum Disorder. The leading methanol sources are cigarette smoke and aspartame (E951). WC Monte gives 745 free full text medical research references at WhileScienceSleeps.com . California OEHHA sets methanol ingestion level 23 mg daily, same as from 1 can aspartame diet soda, 10 cigarettes, 3 tomatoes, or 4 cans green beans: Rich Murray 2013.07.03 http://rmforall.blogspot.com/2013/07/california-oehha-sets-methanol.html "However, the anticipated exposure to methanol from consumption of aspartame would not be considered an exposure within the meaning of Proposition 65 because aspartame is not listed under Proposition 65." [ Rich Murray: Many pregnant women drink one 12-oz can aspartame diet drink daily, with 200 mg aspartame that gives 11% methanol, 22 mg, which is just under the OEHHA limit of 23 mg daily. The smoke from 10 cigarettes gives 20 mg methanol, the same as from  3 full size fresh tomatoes, or 4 cans of unfresh green beans. ] smoke from a pack cigarettes gives 40 mg methanol (wood alcohol), same as from 2 aspartame diet drinks -- becomes formaldehyde inside brain and retina cells via ADH1 enzyme -- WC Monte paradigm: Rich Murray 2013.08.30 11% of aspartame is methanol, which becomes free floating formaldehyde inside human cells -- methanol also in cigarettes and canned fruits and vegetables: Rich Murray 2013.08.30 Human epidemiological studies so far fail to control for additional common methanol sources: cigarettes and wood and peat smoke, smoked foods, fresh tomatoes, and degraded pectins from unfresh fruits juices vegetables preserved wet at room temperature in sealed cans jars plastic containers... autism as a birth defect from epigenetic methylation by formaldehyde made from methanol by ADH1 enzyme inside Purkinje cells in vermis in cerebellum and in inner walls of brain blood vessels -- Prof. WC Monte paradigm: Rich Murray 2013.04.26 http://rmforall.blogspot.com/2013/04/autism-as-birth-defect-from-epigenetic.html CA Pardo autism brain autopsy findings in 2005 fit WC Monte paradigm -- methanol with blood half-life 3 hours is made by ADH1 enzyme into free floating formaldehyde in 20 defenseless human cells in 20 tissues: Rich Murray 2013.07.21 http://rmforall.blogspot.com/2013/07/ca-pardo-autism-brain-autopsy-findings.html The Woodrow C. Monte methanol/formaldehyde toxicity paradigm is that concentrations of ADH1 enzyme, well known to exist inside blood vessel wall cells in specific tissues, quickly turn methanol into formaldehyde inside the vessel cells, in humans only -- the highly reactive formaldehyde diffuses to penetrate adjacent tissue cells, binding to DNA, RNA, and proteins, attracting macrophages, which die, creating complex, expanding micro lesions, leading to many modern "diseases of civilization", Alzheimer's, arthritis, diabetes, multiple sclerosis, lupus -- as well as later cancers -- also serious birth defects in the fetal brain in the fourth week of pregnancy, spinal bifida and autism. Aspartame is 11% methanol, 22 mg per can of diet drink -- similar levels of methanol come from wood and cigarette smoke, heated and canned fruits juices vegetables, fermented and smoked foods, some wines and liquors, vehicle fuels, many cleaners and solvents, chemical medical autopsy mortuary facilities, heated wood in particleboard and paper factories, and more. WC Monte submits robust evidence for multiple sclerosis, which he concludes proves methanol to be the proximate toxic cause, since ADH1 enzyme is within the cells of the inner linings of brain blood vessels, the Purkinje cells of the vermis of the cerebellum, and rods and cones of the retina -- ADH1 quickly turns methanol into free floating formaldehyde within these cells, disrupting the blood brain barrier... See also: James McDonald to EFSA, outdated aspartame ADI gives methanol 35 times too high for human safety, ten minute talk at April 9 public sharing, Brussels: Rich Murray 2013.04.15 http://rmforall.blogspot.com/2013/04/james-mcdonald-to-efsa-outdated.html aspartame harm in rat brain from 75 mg/kg gives human ADI 0.75 mg/kg, 53 times less than EU ADI 40 mg/kg, Ashok Iyyaswamy, SheelaDevi Rathinasamy, U. Madras 2012.08.03 free full text -- main methanol toxin is formaldehyde, not formate: Rich Murray 2013.06.01 http://rmforall.blogspot.com/2013/06/aspartame-harm-in-rat-brain-from-75.html more lower aspartame and methanol ADIs from studies by RH Nair, SheelaDevi Rathinasamy, WC Monte, PS Jeganathan, A Namasivayam, Hazleton Labs, Searle Labs: Rich Murray 2013.06.01 http://rmforall.blogspot.com/2013/06/more-lower-aspartame-and-methanol-adis.html Kate S. Collison et al show prediabetic harm in gene expression in mice fed lifetime aspartame, MSG, trans fats -- reduce human aspartame ADI 1000 times: Rich Murray 2013.07.30 http://rmforall.blogspot.com/2013/07/kate-s-collison-et-al-show-prediabetic.html aspartame impairment of spatial cognition and insulin sensitivity in mice, focus on phenylalanine and aspartate [ methanol also crosses placenta into fetus, turning into teratogenic formaldehyde], Kate S. Collison et al, PLoS One 2012.04.03: Rich Murray 2012.04.29 http://rmforall.blogspot.com/2012/04/aspartame-impairment-of-spatial.html usual doses of aspartame proven to cause cancers, Michael F. Jacobson PhD, Director, Center for Science in the Public Interest -- also long 1985 statement: Rich Murray 2013.08.15 http://rmforall.blogspot.com/2013/08/usual-doses-of-aspartame-proven-to.html highly competent, pithy analysis of aspartame cancer study by Eva S. Schernhammer at Harvard, William R. Ware, PhD, showing relevance of Woodrow C. Monte methanol-formaldehyde toxicity paradigm: Rich Murray 2012.12.03 http://rmforall.blogspot.com/2012/12/highly-competent-pithy-analysis-of.html careful expert lifetime study on mice shows liver and lung cancers from aspartame, M Soffritti et al, Ramazzini Institute, Italy, checked by US National Toxicology Program experts, confirms many previous studies from 2001 on: Rich Murray 2011.02.27 http://rmforall.blogspot.com/2011/02/careful-expert-lifetime-study-on-mice.html The public EFSA session on aspartame safety on April 9 for 5 hours included an audience of about 50 experts and 10-20 ESFA staff in Brussels. The release of the final EFSA review on aspartame safety will be delayed from April 15 to November, 2013. Extremely cogent multiple lines of robust evidence were briefly described that strongly support the methanol formaldehyde toxicity paradigm of Prof. Woodrow C. Monte, Prof. Food Science and Nutrition, Arizona State University, retired 2004 -- supported by an online archive of 745 free full text medical research references at www.WhileScienceSleeps.com . It is clear that methanol is far more dangerous for chronic low level exposures than realized since 1890. Major sources include the smoke from a pack of cigarettes, 40 mg methanol,the same as from 2 cans aspartame diet drink. It now seems likely that most cigarette diseases are actually methanol toxicity... Methanol stays in the blood with a half-life of 3 hours, reaching every part of the body and the fetus with the bloodstream, and readily entering all cells. Humans are uniquely vulnerable to methanol formaldehyde toxicity, as they lack a functioning catalase enzyme system, that in all other creatures serves to protect each cell against the rapid conversion of methanol into free floating formaldehyde right inside the cells of 20 specific tissues that have high levels of ADH1 enzyme. The effects are used to good advantage in embalming and disinfection, as formaldehyde immediately bonds to and impairs DNA, RNA, and proteins, permanently disrupting cell biochemistry, cell by cell, as long as methanol is ingested -- leading to 20 specific chronic modern novel "diseases of civilization", that progress slowly and erratically, according to the ingestion of methanol from a variety of modern sources: smoke from cigarettes, wood, and peat; since 1983, aspartame, including from most chewing gums; fresh tomatoes and black currants; unfresh fruits juices vegetables cut up and preserved wet at room temperature in sealed cans jars plastic containers; jams jellies marmalades; smoked fermented spoiled foods; many dark wines and liquors; work at paper and wood factories, mortuaries, medical and chemical facilities; Research since 2012 specifically shows the presence of formaldehyde bonded to cellular macromolecules inside cells after methanol ingestion -- the paradigm will be confirmed in detail very quickly, as science exponentially explores this simple breakthrough. This presents the world food industry with an unprecedented opportunity to serve the huge public good by collaborating vigorously to eliminate all methanol exposures from foods and beverages. The Net guarantees that the news and evidence will spread explosively everywhere. Paul Thomas MD Pediatrics and Integrative Medicine, Portland OR, praises "While Science Sleeps" at Amazon.com -- WC Monte paradigm of methanol formaldehyde toxicity via ADH1 enzyme in 20 human tissues, including fetus: Rich Murray 2013.04.03 http://rmforall.blogspot.com/2013/04/paul-thomas-md-pediatrics-integrative.html Prof. Resia Pretorius letter re aspartame to EJCN cites Prof. Woodrow C. Monte "While Science Sleeps" text, re methanol/formaldehyde toxicity paradigm: Rich Murray 2012.05.21 http://rmforall.blogspot.com/2012/05/prof-resia-pretorius-letter-re.html Aspartame: The hidden danger [methanol/formaldehyde] in our midst and how it kills us, 12 page review of While Science Sleeps text (Woodrow C Monte), International Health News, whole June issue, Editor: William R Ware PhD: Rich Murray 2012.06.08 http://rmforall.blogspot.com/2012/06/aspartame-hidden-danger.html Table 5.2 is the key chart -- ADH1 enzyme at high levels in 20 tissues in body and fetus makes methanol into formaldehyde right inside cells, initiating over 20 human diseases, with full text references, WC Monte paradigm: Rich Murray 2013.03.21 http://rmforall.blogspot.com/2013/03/table-52-is-key-chart-adh1-enzyme-at.html   "As a matter of course, every soul citizen of Earth has a priority to quickly find and positively share evidence for healthy and safe food, drink, environment, and society." within the fellowship of service, Rich Murray, MA Boston University Graduate School 1967 psychology, BS MIT 1964 history and physics, 254-A Donax Avenue, Imperial Beach, CA 91932-1918, rmforall@gmail.com, 505-819-7388 cell, 619-623-3468 home, http://rmforall.blogspot.com

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