http://www.activistpost.com/2012/04/roundup-herbicide-linked-to-parkinsons.h
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Alarming new research published in the journal Neurotoxicology and
Teratology supports the emerging connection between glyphosate, the active
ingredient in Roundup herbicide, and neurodegenerative conditions such as
Parkinson's disease and Parkinsonian disorders.
Published this month (April, 2012), the new study entitled "Glyphosate
induced cell death through apoptotic and authophagic mechanisms,"
investigated the potential brain-damaging effects of herbicides, which the
authors stated "have been recognized as the main environmental factor
associated with neurodegenerative disorders, such as Parkinson's disease."
They found that glyphosate inhibited the viability of differentiated test
cells (PC12, adrenal medula derived), in both dose-and-time dependent
manners. The researchers also found that "glyphosate induced cell death via
authophagy pathways in addition to activating apoptotic pathways."
Roundup herbicide is now a ubiquitous contaminant in our air, rain,
groundwater, and food, making complete avoidance near impossible. A growing
body of experimental evidence now indicates that it in addition to its
neurotoxicity it also has the following.
Modes of Toxicity
Carcinogen
Endocrine Disruptor
Genotoxic
Biocide
Cytotoxic
Bioaccumulator
Hepatotoxic
Teratrogenic
Clastogenic
Oxidant
Aquacidal
Mutagenic
Aromatase Disruptor
Glutathione Down-regulator
Malondialdehyde Up-regulator
Necrotic
Nephrotoxic
Once marketed as "safe as table salt" by Monsanto, the original patent
holder and manufacturer of this glyphosate-based herbicide, evidence now
indicates it is toxic to human DNA at concentrations diluted 450-fold lower
than used in agricultural applications.
This study only adds to human case reports of glyphosate-poisoning and/or
occupational exposure where neurological damage was a direct consequence. A
2011 case study published in the journal Parkinsonism Related Disorders,
entitled "Parkinsonism after chronic occupational exposure to glyphosate,"
reported the following incident:
Here we report a patient with parkinsonism following chronic occupational
exposure to glyphosate. A previously healthy 44- year-old woman presented
with rigidity, slowness and resting tremor in all four limbs with no
impairment of short-term memory, after sustaining long term chemical
exposure to glyphosate for 3 years as a worker in a chemical factory. The
chemical plant produced a range of herbicides including: glyphosate,
gibberellins, and dimethyl hydrogen phosphite; however, the patient worked
exclusively in the glyphosate production division. She only wore basic
protection such as gloves or a face mask for 50 h each week in the plant
where glyphosate vapor was generated. She frequently felt weak. Two months
before she came to our clinic, she had expe- rienced severe dizziness and
blurred vision.
Another case study published in 2003 reported a case of parkinsonism
subsequent to glyphosate exposure.
These case studies are also backed up by animal research. In the roundworm
model of glyphosate exposure the chemical results in neurodegeneration
directly associated with damage to the dopamine and GABA producing neurons.
In the rat model, glyphosate exposure results in oxidative brain damage,
particularly the substantia nigra, where the highest concentration of
dopamine-producing cells reside, and which is the primary locus of
neurological damage in Parkinson's disease.
This article first appeared at GreenMedInfo. Please visit to access their
vast database of articles and the latest information in natural health.
Ingrid Blank
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