The main reason scientists will not accept case reports on vitamin D improving autism is that scientists know (correctly) that autism is a genetic disease. Everyone knows that genetic diseases are generally incurable because we don't know how to remove the bad genes and insert some good ones. I left medical school thinking of my genome as something I inherited at birth and left to my children in the marriage bed, without giving much thought to what my genome does for me in between.
Think of your genes as the brain of your biochemistry, and, more important, that without a properly functioning genome you would be dead before you finished reading this newsletter. Genes are determining your biochemistry as you read this newest case report, delete it, or forward to a friend whose family is afflicted with autism.
In genetic diseases, genes can be completely missing, anatomically malformed, functionally impaired, or improperly regulated. I believe what vitamin D is doing in these autism cases is improving regulation (vitamin D is having the proper genes being turned on or off as needed by the brain) but I do not know if any permanent improvement in functionality is occurring. However, I do know that the brains of these kids are in a race against time, the longer their brains are autistic, the more likely their brains will be permanently and forever damaged...
read more...
Related Newsletters
Yet Another Autism Case Report
Update on Autism and Vitamin D
A Mother, Her Autistic Son, and Vitamin D
The Tragedy of Autism and the Promise of Vitamin D
Vitamin D Theory of Autism
Read Dr. Cannell's original theory that started it all.
PDF Download
Dr. Cannell's second manuscript on his Vitamin D Theory of Autism as published in Acta Pædiatrica, May 2010.
For those who missed them...
Statements regarding the November 30th IOM Vitamin D Report:
- Vitamin D Council Executive Director Dr. John Cannell
- Vitamin D Council board member and SUNARC Director Dr. William B. Grant
- Author and long-time investigative health journalist Bill Sardi
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Quick Facts
Abnormally-low activated vitamin D levels produce infants with symptoms of autism while abnormally-high levels produce children with personalities the exact opposite of autism - a condition called Williams Syndrome.
Knudtzon J, Aksnes L, Akslen LA, Aarskog D. Elevated 1,25-dihydroxyvitamin D and normocalcaemia in presumed familial Williams syndrome. Clin Genet. 1987 Dec;32(6):369-74.
Mervis CB, Klein-Tasman BP. Williams syndrome: cognition, personality, and adaptive behavior. Ment Retard Dev Disabil Res Rev. 2000;6(2):148-58.
John Cannell MD
Vitamin D Council Executive Director
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